The role of transcriptional ‘futile cycles’ in autophagy and microbial pathogenesis

The role of transcriptional ‘futile cycles’ in autophagy and microbial pathogenesis

Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating preformed autophagy-related (Atg) proteins to r...

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Bibliographic Details
Main Authors: Guowu Hu, Travis McQuiston, Amélie Bernard, Yoon-Dong Park, Jin Qiu, Ali Vural, Nannan Zhang, Scott R. Waterman, Nathan H. Blewett, Timothy G. Myers, John H. Kehrl, Gulbu Uzel, Daniel J. Klionsky, Peter R. Williamson
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-07-01
Series:Microbial Cell
Subjects:
autoimmunity
autophagy
fungus
pathogen
phosphorylation
TOR
translation
virulence
Online Access:http://microbialcell.com/researcharticles/the-role-of-transcriptional-futile-cycles-in-autophagy-and-microbial-pathogenesis/

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http://microbialcell.com/researcharticles/the-role-of-transcriptional-futile-cycles-in-autophagy-and-microbial-pathogenesis/

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