Adverse childhood experiences, daytime salivary cortisol, and depressive symptoms in early adulthood: a longitudinal genetically informed twin study

Abstract Dysregulated hypothalamic–pituitary–adrenal (HPA)-axis function might underlie the relationship between adverse childhood experiences (ACEs) and depression. However, limited research has examined the possible mediating role of the HPA-axis among young people using longitudinal data. Moreove...

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Bibliographic Details
Main Authors: Eleonora Iob, Jessie R. Baldwin, Robert Plomin, Andrew Steptoe
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01538-w