A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist

A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist

Floor-plate-derived extracellular signaling molecules, including canonical axon guidance cues of the Netrin family, control neuronal circuit organization. Despite the importance of the floor plate as an essential signaling center in the developing vertebrate central nervous system, no systematic app...

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Bibliographic Details
Main Authors: Xuefan Gao, Ute Metzger, Paolo Panza, Prateek Mahalwar, Sören Alsheimer, Horst Geiger, Hans-Martin Maischein, Mitchell P. Levesque, Markus Templin, Christian Söllner
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715006592

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http://www.sciencedirect.com/science/article/pii/S2211124715006592

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