ROS-Induced DNA Damage Associates with Abundance of Mitochondrial DNA in White Blood Cells of the Untreated Schizophrenic Patients

Objective. The aim of this study was (1) to examine the leukocyte mtDNA copy number (CN) in unmedicated (SZ (m−)) and medicated (SZ (m+)) male patients with paranoid schizophrenia (SZ) in comparison with the healthy male controls (HC) and (2) to compare the leukocyte mtDNA CN with the content of an...

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Main Authors: I. V. Chestkov, E. M. Jestkova, E. S. Ershova, V. G. Golimbet, T. V. Lezheiko, N. Yu Kolesina, O. A. Dolgikh, V. L. Izhevskaya, G. P. Kostyuk, S. I. Kutsev, N. N. Veiko, S. V. Kostyuk
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/8587475