Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling.

Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling.

The dopamine D2 receptor (DRD2) is a key receptor that mediates dopamine-associated brain functions such as mood, reward, and emotion. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase whose function has been implicated in the brain reward circuit. In this study, we reve...

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Bibliographic Details
Main Authors: Jaehoon Jeong, Young-Un Park, Dae-Kyum Kim, Saebom Lee, Yongdo Kwak, Seol-Ae Lee, Haeryun Lee, Yoo-Hun Suh, Yong Song Gho, Daehee Hwang, Sang Ki Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877277?pdf=render

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http://europepmc.org/articles/PMC3877277?pdf=render

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