Single-cell RNA-seq reveals cellular heterogeneity of mouse carotid artery under disturbed flow

Abstract Disturbed blood flow (d-flow) has been known to induce changes of the cells in the arterial wall, increasing the risk of atherosclerosis. However, the heterogeneity of the vascular cell populations under d-flow remains less understood. To generate d-flow in vivo, partial carotid artery liga...

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Bibliographic Details
Main Authors: Fengchan Li, Kunmin Yan, Lili Wu, Zhong Zheng, Yun Du, Ziting Liu, Luyao Zhao, Wei Li, Yulan Sheng, Lijie Ren, Chaojun Tang, Li Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00567-0