Identification of Fucosylated SERPINA1 as a Novel Plasma Marker for Pancreatic Cancer Using Lectin Affinity Capture Coupled with iTRAQ-Based Quantitative Glycoproteomics

Identification of Fucosylated SERPINA1 as a Novel Plasma Marker for Pancreatic Cancer Using Lectin Affinity Capture Coupled with iTRAQ-Based Quantitative Glycoproteomics

Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the development of effective diagnostic, prognostic and predictive biomarkers for disease management. Aberrantly fucosylated proteins in PC are considered a valuable resource of clinically useful biomarkers. The...

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Bibliographic Details
Main Authors: Chia-Chun Wu, Yu-Ting Lu, Ta-Sen Yeh, Yun-Hsin Chan, Srinivas Dash, Jau-Song Yu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
pancreatic cancer
plasma
glycobiomarker
AAL
iTRAQ-based quantitative proteome
reverse lectin-based ELISA
Online Access:https://www.mdpi.com/1422-0067/22/11/6079

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https://www.mdpi.com/1422-0067/22/11/6079

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