Digoxin Enhances the Anticancer Effect on Non-Small Cell Lung Cancer While Reducing the Cardiotoxicity of Adriamycin

Digoxin Enhances the Anticancer Effect on Non-Small Cell Lung Cancer While Reducing the Cardiotoxicity of Adriamycin

Digoxin is widely used to treat heart failure. Epidemiological studies suggested it might be used as an anticancer drug or sensitizing agent for cancer therapy. Adriamycin is a well-known anticancer drug, but often causes cardiotoxicity which limits its use. We recently investigated the anticancer e...

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Bibliographic Details
Main Authors: Yingying Wang, Qian Ma, Shaolu Zhang, Hongyan Liu, Baoquan Zhao, Bo Du, Wei Wang, Peng Lin, Zhe Zhang, Yuxu Zhong, Dexin Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
digoxin
DNA damage repair
adriamycin
non-small cell lung cancer
decreased cardiotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00186/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00186/full

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