Data-Driven Sequence of Changes to Anatomical Brain Connectivity in Sporadic Alzheimer’s Disease

Data-Driven Sequence of Changes to Anatomical Brain Connectivity in Sporadic Alzheimer’s Disease

Model-based investigations of transneuronal spreading mechanisms in neurodegenerative diseases relate the pattern of pathology severity to the brain’s connectivity matrix, which reveals information about how pathology propagates through the connectivity network. Such network models typically use net...

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Bibliographic Details
Main Authors: Neil P. Oxtoby, Sara Garbarino, Nicholas C. Firth, Jason D. Warren, Jonathan M. Schott, Daniel C. Alexander, For the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Neurology
Subjects:
brain connectivity analysis
data-driven
Alzheimer’s disease
disease progression modeling
graph theory analysis
computational model
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00580/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00580/full

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