Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation.

Our previous study shows that inhibiting activator protein one (AP1) transcription factor function in murine epidermis, using dominant-negative c-jun (TAM67), increases cell proliferation and delays differentiation. To understand the mechanism of action, we compare TAM67 impact in mouse epidermis an...

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Bibliographic Details
Main Authors: Bingshe Han, Ellen A Rorke, Gautam Adhikary, Yap Ching Chew, Wen Xu, Richard L Eckert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359321?pdf=render