The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

ObjectiveSystemic lupus erythematosus (SLE) is a complex autoimmune disease, and various immune cells are involved in the initiation, progression, and regulation of SLE. Our goal was to reveal the chromatin accessibility landscape of peripheral blood mononuclear cells (PBMCs) in SLE patients at sing...

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Bibliographic Details
Main Authors: Haiyan Yu, Xiaoping Hong, Hongwei Wu, Fengping Zheng, Zhipeng Zeng, Weier Dai, Lianghong Yin, Dongzhou Liu, Donge Tang, Yong Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
single-cell chromatin accessible assay
peripheral blood mononuclear cells
transcription factor
marker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.641886/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.641886/full

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