Macrophage Overexpressing NGAL Ameliorated Kidney Fibrosis in the UUO Mice Model

Macrophage Overexpressing NGAL Ameliorated Kidney Fibrosis in the UUO Mice Model

Background/Aims: Alternatively activated macrophages (AAM) have regenerative and anti-inflammatory characteristics. Here, we sought to evaluate whether AAM cell therapy reduces renal inflammation and fibrosis in the unilateral ureteral obstruction (UUO) mice model. Methods: We stabilized macrophages...

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Bibliographic Details
Main Authors: Roser Guiteras, Anna Sola, Maria Flaquer, Georgina Hotter, Joan Torras, Josep Maria Grinyó, Josep Maria Cruzado
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Chronic kidney disease
Alternatively activated macrophages
Macrophage plasticity
Online Access:http://www.karger.com/Article/FullText/479835

Internet

http://www.karger.com/Article/FullText/479835

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