Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

Background Multiple myeloma (MM) remains an incurable disease and oncolytic viruses offer a well-tolerated addition to the therapeutic arsenal. Oncolytic reovirus has progressed to phase I clinical trials and its direct lytic potential has been extensively studied. However, to date, the role for reo...

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Bibliographic Details
Main Authors: Victoria Jennings, Christopher Parrish, Christy Ralph, Alan Melcher, Adel Samson, Gordon Cook, Fiona Errington-Mais, Matt Coffey, Munitta Muthana, Gemma Migneco, Louise M E Müller, Gina B Scott, Jenny Down, Sancha King, Basem Askar, Babatunde Oyajobi, Karen Scott, Emma West, Elizabeth J Ilett, Michelle Lawson
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/3/e001803.full

Internet

https://jitc.bmj.com/content/9/3/e001803.full

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