IL-Y Aggravates Murine Chronic Graft-Versus-Host Disease by Enhancing T and B Cell Responses
IL-Y, a synthetic member of IL-12 cytokine family, was found to exert potent immunosuppressive effects by inhibiting the differentiation and activation of Th1 and Th17 cells. However, the role of IL-Y in the development of chronic graft-versus-host disease (cGVHD) remains unknown. Here, using murine...
Main Authors: | Li Wan, Ziqi Jin, Bo Hu, Kangkang Lv, Lei Lei, Yonghao Liu, Yuan Song, Ying Zhu, Huanle Gong, Mimi Xu, Yuanyuan Du, Yang Xu, Haiyan Liu, Depei Wu, Yuejun Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.559740/full |
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