Endogenous Antioxidant and LOX-Mediated Systems Contribute to the Hepatoprotective Activity of Aqueous Partition of Methanol Extract of Muntingia calabura L. Leaves against Paracetamol Intoxication

Endogenous Antioxidant and LOX-Mediated Systems Contribute to the Hepatoprotective Activity of Aqueous Partition of Methanol Extract of Muntingia calabura L. Leaves against Paracetamol Intoxication

Methanol extract of Muntingia calabura L. (family Muntingiaceae) leaf has been reported to exert various pharmacological activities including hepatoprotection. The present study was carried out to identify the most effective hepatoprotective partition derived from the extract and to determine the me...

Full description

Bibliographic Details
Main Authors: Zainul Amiruddin Zakaria, Nur Diyana Mahmood, Siti Syariah Mamat, Nurliana Nasir, Maizatul Hasyima Omar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
Muntingia calabura leaves
paracetamol-induced hepatotoxicity
hepatoprotective activity
endegenous antioxidant activity
anti-inflammatory activity
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00982/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00982/full

Similar Items