Silencing of Ether à Go-Go 1 by shRNA Inhibits Osteosarcoma Growth and Cell Cycle Progression

Silencing of Ether à Go-Go 1 by shRNA Inhibits Osteosarcoma Growth and Cell Cycle Progression

Recently, a member of the voltage-dependent potassium channel (Kv) family, the Ether à go-go 1 (Eag1) channel was found to be necessary for cell proliferation, cycle progression and tumorigenesis. However, the therapeutic potential of the Eag1 channel in osteosarcoma remains elusive. In the present...

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Bibliographic Details
Main Authors: Jin Wu, Daixing Zhong, Xijin Fu, Qingjun Liu, Liangqi Kang, Zhenqi Ding
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
ether à go-go 1
osteosarcoma
shRNA
cell proliferation
cell cycle
cyclin
Online Access:http://www.mdpi.com/1422-0067/15/4/5570

Internet

http://www.mdpi.com/1422-0067/15/4/5570

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