Overexpression of mfpA Gene Increases Ciprofloxacin Resistance in Mycobacterium smegmatis
Fluoroquinolones (FQs) are antibiotics useful in the treatment of drug-resistant tuberculosis, but FQ-resistant mutants can be selected rapidly. Although mutations in the DNA gyrase are the principal cause of this resistance, pentapeptide proteins have been found to confer low-level FQ resistance in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2021-01-01
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Series: | International Journal of Microbiology |
Online Access: | http://dx.doi.org/10.1155/2021/6689186 |