Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...

Full description

Bibliographic Details
Main Authors: Nicholas E Banovich, Xun Lan, Graham McVicker, Bryce van de Geijn, Jacob F Degner, John D Blischak, Julien Roux, Jonathan K Pritchard, Yoav Gilad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4169251?pdf=render

Internet

http://europepmc.org/articles/PMC4169251?pdf=render

Similar Items