Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4169251?pdf=render |