Discovery of Three 22-Membered Macrolides by Deciphering the Streamlined Genome of Mangrove-Derived Streptomyces sp. HM190

Discovery of Three 22-Membered Macrolides by Deciphering the Streamlined Genome of Mangrove-Derived Streptomyces sp. HM190

Strain HM190, a moderate halophile, was isolated from rhizosphere soil of the mangrove Kandelia obovata in Fugong village, China. The 16S ribosomal RNA (rRNA) gene sequence and the results of phylogenetic analysis revealed that strain HM190 belonged to the genus Streptomyces and had the highest sequ...

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Bibliographic Details
Main Authors: Yanghui Ye, Nusratgul Anwar, Xuming Mao, Shihua Wu, Cen Yan, Zhe Zhao, Ran Zhang, Yanfang Nie, Jianwei Zhang, Jidong Wang, Min Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
Streptomyces sp. HM190
biosynthetic gene clusters
22-membered macrolides
structure elucidation
cytotoxic activities
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01464/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01464/full

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