Pathway-based biomarker identification with crosstalk analysis for robust prognosis prediction in hepatocellular carcinomaResearch in context

Background: Although many prognostic single-gene (SG) lists have been identified in cancer research, application of these features is hampered due to poor robustness and performance on independent datasets. Pathway-based approaches have thus emerged which embed biological knowledge to yield reproduc...

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Bibliographic Details
Main Authors: Botao Fa, Chengwen Luo, Zhou Tang, Yuting Yan, Yue Zhang, Zhangsheng Yu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419303111