Restoration of CMV-specific-CD4 T cells with ART occurs early and is greater in those with more advanced immunodeficiency.

Restoration of CMV-specific-CD4 T cells with ART occurs early and is greater in those with more advanced immunodeficiency.

Restoration of Cytomegalovirus-specific-CD4 T cell (CMV-Sp-CD4) responses partly accounts for the reduction of CMV-disease with antiretroviral-therapy (ART), but CMV-Sp-CD4 may also drive immune activation and immunosenescence. This study characterized the dynamics of CMV-Sp-CD4 after ART initiation...

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Bibliographic Details
Main Authors: Denise C Hsu, Stephen J Kerr, Thatri Iampornsin, Sarah L Pett, Anchalee Avihingsanon, Parawee Thongpaeng, John J Zaunders, Sasiwimol Ubolyam, Jintanat Ananworanich, Anthony D Kelleher, David A Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795037?pdf=render

Internet

http://europepmc.org/articles/PMC3795037?pdf=render

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