Review: Autosomal Dominant Polycystic Kidney Disease: Role of the Renin-Angiotensin System in Raised Blood Pressure in Progression of Renal and Cardiovascular Disease

Raised blood pressure (BP) is extremely common in individuals with autosomal dominant polycystic kidney disease (ADPKD) and is almost invariably raised once they develop renal failure. The underlying mechanisms for the rise in BP in individuals with ADPKD are unclear. The progressive number and enla...

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Bibliographic Details
Main Authors: Catherine R Lawson, Timothy W Doulton, Graham A MacGregor
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.023