Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes

Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes

Type I diabetes (T1D) is a T cell-driven autoimmune disease that results in the killing of pancreatic β-cells and, consequently, loss of insulin production. Using the multiple low-dose streptozotocin (MLD-STZ) model of experimental autoimmune diabetes, we previously reported that pretreatment with a...

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Bibliographic Details
Main Authors: Maria J. Fernández-Cabezudo, Junu A. George, Ghada Bashir, Yassir A. Mohamed, Alreem Al-Mansori, Mohammed M. Qureshi, Dietrich E. Lorke, Georg Petroianu, Basel K. al-Ramadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
cholinergic stimulation
acetylcholine
muscarinic AChR
neuroimmunology
type I diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01038/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01038/full

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