CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

Herpesviruses infect the majority of the human population and can cause significant morbidity and mortality. Herpes simplex virus (HSV) type 1 causes cold sores and herpes simplex keratitis, whereas HSV-2 is responsible for genital herpes. Human cytomegalovirus (HCMV) is the most common viral cause...

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Bibliographic Details
Main Authors: Ferdy R van Diemen, Elisabeth M Kruse, Marjolein J G Hooykaas, Carlijn E Bruggeling, Anita C Schürch, Petra M van Ham, Saskia M Imhof, Monique Nijhuis, Emmanuel J H J Wiertz, Robert Jan Lebbink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005701

Internet

https://doi.org/10.1371/journal.ppat.1005701

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