Comprehensive spectral identification of key intermediates to the final product of the chiral pool synthesis of radezolid
Abstract Radezolid (RAD, 12), biaryl oxazolidinone, was synthesised with small modifications according to the methods described in the literature. The pharmacological activity is observed only for (S)-enantiomer, therefore its synthesis is oriented towards obtaining a single isomer of required purit...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-08-01
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| Series: | Chemistry Central Journal |
| Online Access: | http://link.springer.com/article/10.1186/s13065-017-0309-x |