Preparation and Characterization of Celecoxib Agglomerated Nanocrystals and Dry Powder Inhalation Formulations to Improve its Aerosolization Performance

Background: Celecoxib is a non-steroidal anti-inflammatory drug used extensively in the treatment of pain, arthritis, and cancers. However, its administration is limited due to its several disadvantages including gastric irritation and hepatic first pass metabolism. Among numerous methods for pulmon...

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Bibliographic Details
Main Author: Sepideh Mardani 1, Maryam Maghsoodi 2 * , Saeed Ghanbarzadeh 3,4, Ali Nokhodchi 5, Shadi Yaqoubi 6, Hamed Hamishehkar 7 *
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-12-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:http://journals.tbzmed.ac.ir/PHARM/Abstract/PHARM_827_20170513121959