Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

Abstract Background The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine, alcohol use changes the microbiome composition and increases gut permeability allowing translocation of microbial components in...

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Bibliographic Details
Main Authors: Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, Gyongyi Szabo
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Neuroinflammation
Subjects:
Neuroinflammation
Alcohol
Microglia
Cytokines
Microbiome
Inflammasome
Online Access:http://link.springer.com/article/10.1186/s12974-018-1328-9

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http://link.springer.com/article/10.1186/s12974-018-1328-9

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