Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression
Abstract Background The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine, alcohol use changes the microbiome composition and increases gut permeability allowing translocation of microbial components in...
Main Authors: | Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, Gyongyi Szabo |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1328-9 |
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