Pathological changes in pulmonary circulation in carbon tetrachloride (CCl4)-induced cirrhotic mice.

Pathological changes in pulmonary circulation in carbon tetrachloride (CCl4)-induced cirrhotic mice.

Lack of an experimental model of portopulmonary hypertension (POPH) has been a major obstacle in understanding of pathophysiological mechanisms underlying the disease.We investigated the effects of CCl4-mediated cirrhosis on the pulmonary vasculature, as an initial step towards an improved understan...

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Bibliographic Details
Main Authors: Mita Das, Marjan Boerma, Jessica R Goree, Elise G Lavoie, Michel Fausther, Igor B Gubrij, Amanda K Pangle, Larry G Johnson, Jonathan A Dranoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3999097?pdf=render

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http://europepmc.org/articles/PMC3999097?pdf=render

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