Predicting multi-level drug response with gene expression profile in multiple myeloma using hierarchical ordinal regression

Predicting multi-level drug response with gene expression profile in multiple myeloma using hierarchical ordinal regression

Abstract Background Multiple myeloma (MM), like other cancers, is caused by the accumulation of genetic abnormalities. Heterogeneity exists in the patients’ response to treatments, for example, bortezomib. This urges efforts to identify biomarkers from numerous molecular features and build predictiv...

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Bibliographic Details
Main Authors: Xinyan Zhang, Bingzong Li, Huiying Han, Sha Song, Hongxia Xu, Yating Hong, Nengjun Yi, Wenzhuo Zhuang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Gene expression
Hierarchical ordinal regression
Multiple myeloma
Multi-level drug response
Prediction
Online Access:http://link.springer.com/article/10.1186/s12885-018-4483-6

Internet

http://link.springer.com/article/10.1186/s12885-018-4483-6

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