Detection of microsatellite instability but not truncating APC mutations in gastric adenocarcinomas in Brazilian patients

A crucial role for the adenomatous polyposis colonic (APC) gene in colorectal carcinogenesis has been conclusively established, but, the role of APC in gastric tumors remains controversial. APC mutations have been detected at a relatively high frequency in gastric tumors of Japanese patients, yet su...

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Bibliographic Details
Main Authors: Roberta A.U. Bevilacqua, Cassandra M. Corvello, Ana Paula Duarte, Andrew J.G. Simpson
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2000-06-01
Series:Genetics and Molecular Biology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200001