Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients.

Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients.

Impaired suppressive capacity of CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) from peripheral blood of patients with multiple sclerosis (MS) has been reported by multiple laboratories. It is, however, currently unresolved whether Treg dysfunction in MS patients is limited to reduced control of pe...

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Bibliographic Details
Main Authors: Benedikt Fritzsching, Jürgen Haas, Fatima König, Pierre Kunz, Eva Fritzsching, Johannes Pöschl, Peter H Krammer, Wolfgang Brück, Elisabeth Suri-Payer, Brigitte Wildemann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060879?pdf=render

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http://europepmc.org/articles/PMC3060879?pdf=render

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