Local Efficacy of Glutamate Uptake Decreases with Synapse Size

Local Efficacy of Glutamate Uptake Decreases with Synapse Size

Summary: Synaptically released glutamate is largely cleared by glutamate transporters localized on perisynaptic astrocyte processes. Therefore, the substantial variability of astrocyte coverage of individual hippocampal synapses implies that the efficacy of local glutamate uptake and thus the spatia...

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Bibliographic Details
Main Authors: Michel K. Herde, Kirsten Bohmbach, Cátia Domingos, Natascha Vana, Joanna A. Komorowska-Müller, Stefan Passlick, Inna Schwarz, Colin J. Jackson, Dirk Dietrich, Martin K. Schwarz, Christian Henneberger
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Cell Reports
Subjects:
glutamate uptake
astrocytes
hippocampus
astrocyte morphology
spine morphology
multiphoton imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720311712

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http://www.sciencedirect.com/science/article/pii/S2211124720311712

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