Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway

Long Noncoding RNA SNHG12 Promotes Gastric Cancer Proliferation by Binding to HuR and Stabilizing YWHAZ Expression Through the AKT/GSK-3β Pathway

BackgroundGastric cancer (GC) is a malignancy with high morbidity and mortality rates worldwide. SNHG12 is a long noncoding RNA (lncRNA) commonly involved many types of cancers in the contexts of tumorigenesis, migration and drug resistance. Nevertheless, its role in GC proliferation is poorly under...

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Bibliographic Details
Main Authors: Tianqi Zhang, Maneesh Kumarsing Beeharry, Yanan Zheng, Zhenqiang Wang, Jianfang Li, Zhenggang Zhu, Chen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
proliferation
SNHG12
HuR
YWHAZ
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.645832/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.645832/full

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