Effects of HDAC4 on IL-1β-induced matrix metalloproteinase expression regulated partially through the WNT3A/β-catenin pathway

Abstract. Background:. Histone deacetylase 4 (HDAC4) regulates chondrocyte hypertrophy and bone formation. The aim of the present study was to explore the effects of HDAC4 on Interleukin 1 beta (IL-1β)-induced chondrocyte extracellular matrix degradation and whether it is regulated through the WNT f...

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Bibliographic Details
Main Authors: Qi Ning, Ye-Hua Gan, Rui-Rui Shi, Juan-Hong Meng, Xiu-Yuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2021-04-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001470