Poly(lysine) Dendrimers Form Complexes with siRNA and Provide Its Efficient Uptake by Myeloid Cells: Model Studies for Therapeutic Nucleic Acid Delivery

The disruption of the cellular pathways of protein biosynthesis through the mechanism of RNA interference has been recognized as a tool of great diagnostic and therapeutic significance. However, in order to fully exploit the potential of this phenomenon, efficient and safe carriers capable of overco...

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Bibliographic Details
Main Authors: Michał Gorzkiewicz, Olga Kopeć, Anna Janaszewska, Małgorzata Konopka, Elżbieta Pędziwiatr-Werbicka, Irina I. Tarasenko, Valeriy V. Bezrodnyi, Igor M. Neelov, Barbara Klajnert-Maculewicz
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/9/3138