Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2.

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The myogenic lineage colonizes pre-...

Full description

Bibliographic Details
Main Authors: Adam L Campbell, Hung-Ping Shih, Jun Xu, Michael K Gross, Chrissa Kioussi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338778?pdf=render