Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice

Abstract Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs...

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Bibliographic Details
Main Authors: Daniel Balazs Fulop, Viktoria Humli, Judit Szepesy, Virag Ott, Dora Reglodi, Balazs Gaszner, Adrienn Nemeth, Agnes Szirmai, Laszlo Tamas, Hitoshi Hashimoto, Tibor Zelles, Andrea Tamas
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50775-z