Penetrance estimates for <it>BRCA1 </it>and <it>BRCA2 </it>based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

<p>Abstract</p> <p>Background</p> <p>The identification of a <it>BRCA1 </it>or <it>BRCA2 </it>mutation in familial breast cancer kindreds allows genetic testing of at risk relatives. However, considerable controversy exists regarding the cancer r...

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Bibliographic Details
Main Authors: Lalloo Fiona, Woodward Emma, Shenton Andrew, Evans D Gareth, Howell Anthony, Maher Eamonn R
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/155