Identification of Key Functional Gene Signatures Indicative of Dedifferentiation in Papillary Thyroid Cancer

Identification of Key Functional Gene Signatures Indicative of Dedifferentiation in Papillary Thyroid Cancer

Background: Differentiated thyroid cancer (DTC) is the most common type of thyroid cancer. Many of them can relapse to dedifferentiated thyroid cancer (DDTC) and exhibit different gene expression profiles. The underlying mechanism of dedifferentiation and the involved genes or pathways remained to b...

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Bibliographic Details
Main Authors: Weibo Xu, Cuiwei Li, Ben Ma, Zhongwu Lu, Yuchen Wang, Hongyi Jiang, Yi Luo, Yichen Yang, Xiao Wang, Tian Liao, Qinghai Ji, Yu Wang, Wenjun Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
papillary thyroid cancer
dedifferentiation
functional grouping
gene signature
LASSO
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.641851/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.641851/full

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