Oculus: faster sequence alignment by streaming read compression

<p>Abstract</p> <p>Background</p> <p>Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alig...

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Bibliographic Details
Main Authors: Veeneman Brendan A, Iyer Matthew K, Chinnaiyan Arul M
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2105/13/297