Predicting rifampicin resistance mutations in bacterial RNA polymerase subunit beta based on majority consensus
Abstract Background Mutations in an enzyme target are one of the most common mechanisms whereby antibiotic resistance arises. Identification of the resistance mutations in bacteria is essential for understanding the structural basis of antibiotic resistance and design of new drugs. However, the trad...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04137-0 |