Predicting rifampicin resistance mutations in bacterial RNA polymerase subunit beta based on majority consensus

Abstract Background Mutations in an enzyme target are one of the most common mechanisms whereby antibiotic resistance arises. Identification of the resistance mutations in bacteria is essential for understanding the structural basis of antibiotic resistance and design of new drugs. However, the trad...

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Bibliographic Details
Main Authors: Qing Ning, Dali Wang, Fei Cheng, Yuheng Zhong, Qi Ding, Jing You
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04137-0