LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway

LncRNA-NEAT1 from the competing endogenous RNA network promotes cardioprotective efficacy of mesenchymal stem cell-derived exosomes induced by macrophage migration inhibitory factor via the miR-142-3p/FOXO1 signaling pathway

Abstract Aims Extracellular vesicles, especially exosomes, have emerged as key mediators of intercellular communication with the potential to improve cardiac function as part of cell-based therapies. We previously demonstrated that the cardioprotective factor, macrophage migration inhibitory factor...

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Bibliographic Details
Main Authors: Hanbin Chen, Wenzheng Xia, Meng Hou
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Exosome
MIF
Cardiomyocytes apoptosis
LncRNA-NEAT1/miR-142-3p/FOXO1 signaling pathway
Oxidative stress
Online Access:https://doi.org/10.1186/s13287-020-1556-7

Internet

https://doi.org/10.1186/s13287-020-1556-7

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