Verapamil Inhibits Mitochondria-Induced Reactive Oxygen Species and Dependent Apoptosis Pathways in Cerebral Transient Global Ischemia/Reperfusion

The prefrontal cortex is the largest lobe of the brain and is consequently involved in stroke. There is no comprehensive practical pharmacological strategy for ameliorating prefrontal cortex injury induced by cerebral ischemia. Therefore, we studied the neuroprotective properties of verapamil (Ver)...

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Main Authors: Ehsan Jangholi, Zahra Nadia Sharifi, Mohammad Hoseinian, Mohammad-Reza Zarrindast, Hamid Reza Rahimi, Ashkan Mowla, Hoda Aryan, Mohammad Amin Javidi, Yekta Parsa, Fariborz Ghaffarpasand, Soheila Yadollah-Damavandi, Hamid Zaferani Arani, Farshad Shahi, Shabnam Movassaghi
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/5872645