Transplanted Dentate Progenitor Cells Show Increased Survival in an Enriched Environment but Do Not Exert a Neurotrophic Effect on Spatial Memory within 2 Weeks of Engraftment

Cyclin D2 knockout mice show decreased levels of endogenous dentate neurogenesis. We investigated whether transplanted dentate progenitor cells from wild-type mice respond in vivo to an enriched environment and whether they improve deficient dentate neurogenesis through a neurotrophic effect. Adult...

Full description

Bibliographic Details
Main Authors: Amanda L. Jamal, Tara L. Walker, Amanda J. Waber Nguyen, Robert F. Berman, Gerd Kempermann, Ben Waldau M.D.
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X687011