Intrinsic optical signal imaging and targeted injections through a chronic cranial window of a head-fixed mouse

Summary: Intrinsic optical signal imaging (ISI) is a hemodynamic response-based technique to map the functional architecture of the cortex. ISI is often used as an auxiliary method to localize cortical areas for targeted electrophysiology, pharmacology, or imaging experiments. Here, we provide a pro...

Full description

Bibliographic Details
Main Authors: Sigita Augustinaite, Bernd Kuhn
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721004858