Nitric oxide signalling modulates synaptic inhibition in the superior paraolivary nucleus (SPN) via cGMP-dependent suppression of KCC2

Nitric oxide signalling modulates synaptic inhibition in the superior paraolivary nucleus (SPN) via cGMP-dependent suppression of KCC2

Glycinergic inhibition plays a central role in the auditory brainstem circuitries involved in sound localization and in the encoding of temporal action potential firing patterns. Modulation of this inhibition has the potential to fine-tune information processing in these networks. Here we show that...

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Bibliographic Details
Main Authors: Lina eYassin, Susanne eRadtke-Schuller, Hila eAsraf, Benedikt eGrothe, Michal eHershfinkel, Ian D Forsythe, Conny eKopp-Scheinpflug
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Neural Circuits
Subjects:
Nitric Oxide
Zinc
KCC2
gap detection
lateral superior olive
medial nucleus of the trapezoid body
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00065/full

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http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00065/full

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