The Natural Selection of Herpesviruses and Virus-Specific NK Cell Receptors

During the co-evolution of cytomegalovirus (CMV) and natural killer (NK) cells, each has evolved specific tactics in an attempt to prevail. CMV has evolved multiple immune evasion mechanisms to avoid detection by NK cells and other immune cells, leading to chronic infection. Meanwhile, the host has...

Full description

Bibliographic Details
Main Authors: Joseph C. Sun, Lewis L. Lanier
Format: Article
Language:English
Published: MDPI AG 2009-10-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/1/3/362/