Celastrol Prevents Oxidative Stress Effects on FSHR, PAPP, and CYP19A1 Gene Expression in Cultured Human Granulosa-Lutein Cells

Celastrol Prevents Oxidative Stress Effects on FSHR, PAPP, and CYP19A1 Gene Expression in Cultured Human Granulosa-Lutein Cells

Regulation of oxidative stress (OS) is important to prevent damage to female reproductive physiology. While normal OS levels may have a regulatory role, high OS levels may negatively affect vital processes such as folliculogenesis or embryogenesis. The aim of this work was to study OS induced by glu...

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Bibliographic Details
Main Authors: Rita Martín-Ramírez, Rebeca González-Fernández, Deborah Rotoli, Jairo Hernández, Pablo Martín-Vasallo, Angela Palumbo, Julio Ávila
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
granulosa-lutein cells
oxidative stress
reactive oxygen species
reactive nitrogen species
celastrol
Online Access:https://www.mdpi.com/1422-0067/22/7/3596

Internet

https://www.mdpi.com/1422-0067/22/7/3596

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