Characterization of M. tuberculosis SerB2, an essential HAD-family phosphatase, reveals novel properties.

M. tuberculosis harbors an essential phosphoserine phosphatase (MtSerB2, Rv3042c) that contains two small- molecule binding ACT-domains (Pfam 01842) at the N-terminus followed by the phosphoserine phosphatase (PSP) domain. We found that exogenously added MtSerB2 elicits microtubule rearrangements in...

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Bibliographic Details
Main Authors: Gaya Prasad Yadav, Sonal Shree, Ruchi Maurya, Niyati Rai, Diwakar Kumar Singh, Kishore Kumar Srivastava, Ravishankar Ramachandran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4270767?pdf=render